Monday, August 9, 2010

The Benzyne Mechanism

Unactivated halogens in aromatic compound undergo indirect nucleophilic displacement in presence of very strong base, which is clearly different from the SNAr mechanism . The mechanism followed by such reaction is known as Benzyne Mechanism.
The intresting features of benzyne mechanism is that the incoming group does not always take the position vacated by the leaving group. This reactions involved elimination on followed by addition . The intermediate molecule is called Benzyne .

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